학술논문

Intra-vaginal prostaglandin E2 versus double-balloon catheter for labor induction in term oligohydramnios.
Document Type
Article
Source
Journal of Perinatology. Feb2015, Vol. 35 Issue 2, p95-98. 4p. 3 Charts.
Subject
*INDUCED labor (Obstetrics)
*AMNIOTIC liquid
*CATHETERIZATION
*CHI-squared test
*PREGNANCY complications
*PROSTAGLANDINS
*T-test (Statistics)
*RANDOMIZED controlled trials
*DESCRIPTIVE statistics
*MANN Whitney U Test
Language
ISSN
0743-8346
Abstract
Objective:Compare mechanical and pharmacological ripening for patients with oligohydramnios at term.Study design:Fifty-two patients with oligohydramnios ⩽5 cm and Bishop score ⩽6 were randomized for labor induction with a vaginal insert containing 10 mg timed-release dinoprostone (PGE2) or double-balloon catheter. The primary outcome was time from induction to active labor. Time to labor, neonatal outcomes and maternal satisfaction were also compared.Result:Baseline characteristics were similar. Time from induction to active labor (13 with PGE2 vs 19.5 h with double-balloon catheter; P=0.243) was comparable, with no differences in cesarean rates (15.4 vs 7.7%; P=0.668) or neonatal outcomes. The PGE2 group had higher incidence of early device removal (76.9 vs 26.9%; P=0.0001), mostly because of active labor or non-reassuring fetal heart rate. Fewer PGE2 patients required oxytocin augmentation for labor induction (53.8 vs 84.6% P=0.034). Time to delivery was significantly shorter with PGE2 (16 vs 20.5 h; P=0. 045)Conclusion:Intravaginal PGE2 and double-balloon catheter are comparable methods for cervical ripening in term pregnancies with oligohydramnios. [ABSTRACT FROM AUTHOR]