부산대학교 도서관

Leptospirosis is a ubiquitous zoonotic infection caused by bacterial spirochetes that are equally adapted to life in the aqueous environment as they are to infection of their eucaryotic hosts. The open pan-genome reflects the leptospiral life cycle, which includes the ability of leptospiral pathogens to form biofilms to withstand environmental stress and survive for prolonged periods in milieux such as soil and aqueous habitats [[6]]. Genome sequence of the saprophyte Leptospira biflexa provides insights into the evolution of Leptospira and the pathogenesis of leptospirosis. (B) Distribution of gene clusters in the P1 clade revealing an open pan-genome with a relatively high number of gene clusters found only in a single species. [Extracted from the article]