부산대학교 도서관

Keywords: sexually transmitted infection; solid organ transplantation; syphilis EN sexually transmitted infection solid organ transplantation syphilis 1 3 3 02/10/22 20220201 NES 220201 Dear Editor, Sexually transmitted infections (STIs) have reached a new all-time high, affecting one in five people in the United States on any given day.1,2 For syphilis alone, there has been a 70% increase in cases between 2015 and 2019, including a 279% increase in congenital syphilis.2 Despite this, the epidemiology and clinical presentation of STIs among immunosuppressed solid organ transplant (SOT) patients are poorly understood. Given the immediate treatment post-transplantation, donor-derived syphilis cases are often asymptomatic, but recipients will demonstrate seroconversion.8,9 One report describes a lung transplant recipient with isolated immunoglobulin-G (IgG) seroconversion after receipt of lungs from a donor with serologic evidence of past syphilis infection.7 As a common and easily treatable infection, syphilis should not be forgotten outside of the peri-transplant period. Delayed diagnosis and treatment of secondary syphilis in pancreas-kidney transplant recipient: Need for increased awareness of sexually transmitted infections in solid organ transplantation In contrast, while bone involvement with syphilis is associated with congenital and tertiary syphilis, it is an unusual finding in secondary syphilis,12 as evidenced by a retrospective series of 854 patients with secondary syphilis finding that only 0.2% of patients had bone lesions.13 Clinicians should be aware of diagnostic bias that presents when treating SOT patients. [Extracted from the article]