학술논문

Evaluation of a new rapid immunoassay for the detection ofHelicobacter pyloriin faeces: a prospective pilot study.
Document Type
Article
Source
Alimentary Pharmacology & Therapeutics. Feb2005, Vol. 21 Issue 4, p485-489. 5p.
Subject
*ENZYME-linked immunosorbent assay
*IMMUNOASSAY
*HELICOBACTER pylori
*DIAGNOSIS
*FECES
*HISTOLOGY
*BIOPSY
Language
ISSN
0269-2813
Abstract
: Detection ofHelicobacter pyloriantigen in faeces is a valid method to diagnoseH. pyloriinfection. Presently available stool tests are performed in the laboratory, and diagnostic report is delayed.: To evaluate a new rapid stool test in a pre-treatment setting and to compare it with a validated laboratory stool test.: A total of 105 patients underwent gastroscopy with brush cytology, and biopsies for histology and rapid urease test, to assessH. pyloripresence.Helicobacter pylori-status was considered positive if at least two tests were positive; negative if all tests were negative; indeterminate if one test was positive and two negative. Stool specimens were tested using either a rapid immunoassay kit (ImmunoCard STAT) or a laboratory enzyme immunoassay kit (Hp StAR).: Sixty patients were infected withH. pylori, 44 non-infected, one indeterminate. The sensitivity and specificity of ImmunoCard STAT were 85 and 93%; those of Hp StAR were 88 and 100% (not significant).: ImmunoCard STAT seems a reliable method for detectingH. pyloriin untreated patients. It could replace laboratory stool tests, as it is easy and can be performed quickly. These characteristics might be a breakthrough for diagnosingH. pyloriin the doctor's office. [ABSTRACT FROM AUTHOR]