부산대학교 도서관

Key content: Antenatal corticosteroids (ACS) are a key evidence‐based intervention proven to reduce neonatal morbidity and mortality.ACS should be given in a timely manner to ensure maximal benefit. This can be challenging, particularly in women presenting with suspected spontaneous preterm labour.There is continuing uncertainty about the role of repeat ACS courses in women who remain at high risk of preterm delivery.Evidence from long‐term follow‐up studies has yielded mixed findings; further research is needed to determine the impact of ACS on future health. Learning objectives: To understand the mechanisms underpinning ACS effectiveness in utero and the evidence to support their use.To understand the rationale for ACS use in specific circumstances, as well as current areas of uncertainty. Ethical issues: For women who receive ACS for threatened preterm labour, there is only benefit if their baby is born within 7 days. Therefore, optimal prediction of risk of preterm delivery is essential.Evidence of benefit of ACS does not translate directly from high‐income settings into low‐ and middle‐income countries because there are other factors that influence preterm birth outcomes.Timing of ACS, in relation to time before delivery, number of courses and gestational age, is likely to be important. [ABSTRACT FROM AUTHOR]