학술논문

Khat Chewing from the Pharmacological Point of View: An Update.
Document Type
Article
Source
Substance Use & Misuse. 2008, Vol. 43 Issue 6, p762-783. 22p. 2 Charts.
Subject
*KHAT
*ENDEMIC plants
*DRUG traffic
*SUBSTANCE abuse
*PHARMACEUTICAL policy
*PUBLIC health
*BREWERIES
*AMPHETAMINES
Language
ISSN
1082-6084
Abstract
Khat chewing is deeply rooted in the every day life of people living in the Horn of Africa and in South Arabia, where Catha edulis is endemic. Considered little more than an exotic habit producing just mild pharmacological effects, systematic investigations on its active principles have instead lead to the isolation and chemical characterization of cathinone, a compound structurally related to amphetamine. Three decades of intense experimental and clinical research on khat have depicted a consistently clear picture of its pharmacological and toxicological effects. [ABSTRACT FROM AUTHOR]