학술논문

Diffusion-weighted magnetic resonance imaging is useful for assessing inflammatory myopathies.
Document Type
Journal Article
Source
Muscle & Nerve. May2019, Vol. 59 Issue 5, p555-560. 6p.
Subject
*COMPARATIVE studies
*CREATINE kinase
*DERMATOMYOSITIS
*DIAGNOSTIC imaging
*EDEMA
*ENZYMES
*MAGNETIC resonance imaging
*RESEARCH methodology
*MEDICAL cooperation
*MYOSITIS
*POLYMYOSITIS
*RESEARCH
*RESEARCH funding
*INCLUSION body myositis
*EVALUATION research
*RETROSPECTIVE studies
*CASE-control method
*SKELETAL muscle
Language
ISSN
0148-639X
Abstract
Introduction: Short tau inversion recovery (STIR) sequences in whole-body MRI are usually used for detecting muscle edema (ME) in inflammatory myopathies. We evaluated b-value 800 diffusion-weighted imaging (b800 DWI).Methods: Two radiologists independently and a consensus reader retrospectively reexamined 60 patients with inflammatory myopathies and 15 controls. For each participant, 78 muscles were analyzed with 3 sets of imaging acquisitions: T1-weighted (T1) turbo spin echo and STIR; T1 and DWI; and T1, STIR and DWI. Mean edema per patient was compared between sequences. Agreement was evaluated.Results: Diffusion-weighted imaging detected more ME compared with STIR (P < 0.001). Agreement between readers was better with both sequences (k = 0.94) than with b800 DWI (k = 0.89) or STIR (k = 0.84) alone.Discussion: Diffusion-weighted imaging is a valuable add-on for the study of inflammatory myopathies. Muscle Nerve 59:555-555, 2019. [ABSTRACT FROM AUTHOR]