학술논문
Genome-wide characterization of Mediator recruitment, function, and regulation.
Document Type
Article
Source
Subject
*GENOMES
*GENETIC transcription regulation
*TRANSCRIPTION factors
*TRANS-regulatory elements (Genetics)
*RNA polymerases
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Language
ISSN
2154-1264
Abstract
Mediator is a conserved and essential coactivator complex broadly required for RNA polymerase II (RNAPII) transcription. Recent genome-wide studies of Mediator binding in budding yeast have revealed new insights into the functions of this critical complex and raised new questions about its role in the regulation of gene expression. [ABSTRACT FROM PUBLISHER]