학술논문
Invasive measurement of portal hypertension in the hemodynamics laboratory as an important element of qualification for the treatment of esophageal varices: A single-center experience.
Document Type
Article
Author
Source
Subject
*ESOPHAGEAL varices
*PORTAL hypertension
*HEMODYNAMICS
*PROGNOSIS
*CIRRHOSIS of the liver
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Language
ISSN
1230-8013
Abstract
Introduction: The measurement of hepatic venous pressure gradient (HVPG) is an essential prognostic factor in subjects with chronic liver disorders. Aim: The present study aimed to present the feasibility and applicability of HVPG in the modern hemodynamics laboratory in patients with liver cirrhosis as a stage for qualification in variceal band ligation (VBL). Material and methods : We included 78 patients with liver cirrhosis and esophageal varices, who had HVPG measurements taken at the hemodynamics laboratory between January 2015 and January 2019. Results and discussion: The mean age was 55.5 ± 10.9 years, and 66.7% were males. The most common cause of liver cirrhosis was alcohol abuse (65.4%), and the most common varices stage was 3 (83.3%). The mean HVPG was 16.3 ± 6.2 mm Hg. In total, 67 (85.9%) patients had HVPG over 10 mm Hg and underwent VBL. No periprocedural complications were observed. At 12 months, recurrent hospitalizations were observed in 67 (85.9%), 5 (6.4%)had cirrhosis- -related bleeding episodes, and 4 (5.1%) patients died. Conclusions : HVPG measurement is a feasible, safe and reproducible procedure that provides valuable diagnostic/prognostic information and helps make therapeutic decisions. This procedure can be done quickly in the modern hemodynamics laboratory. [ABSTRACT FROM AUTHOR]