학술논문
Diagnosis and Treatment of Paraneoplastic Neurologic Syndromes.
Document Type
Article
Source
Subject
*PARANEOPLASTIC syndromes
*PERIPHERAL nervous system
*DIAGNOSIS
*ANTIBODY formation
*CENTRAL nervous system
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Language
ISSN
2073-4468
Abstract
Paraneoplastic antibody syndromes result from the anti-tumor antibody response against normal antigens ectopically expressed by tumor cells. Although this antibody response plays an important role in helping clear a nascent or established tumor, the engagement of antigens expressed in healthy tissues can lead to complex clinical syndromes with challenging diagnosis and management. The majority of known paraneoplastic antibody syndromes have been found to affect the central and peripheral nervous system. The present review provides an update on the pathophysiology of paraneoplastic neurologic syndromes, as well as recommendations for their diagnosis and treatment. [ABSTRACT FROM AUTHOR]