학술논문
Neuropsychological and clinical findings of Cognitive Remediation Therapy feasibility randomised controlled trial in young people with anorexia nervosa.
Document Type
Article
Author
Source
Subject
*ANOREXIA nervosa treatment
*NEUROPSYCHOLOGY
*ANALYSIS of variance
*RANDOMIZED controlled trials
*AUTISM
*REPEATED measures design
*QUESTIONNAIRES
*DESCRIPTIVE statistics
*STATISTICAL sampling
*DATA analysis software
*COGNITIVE therapy
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Language
ISSN
1072-4133
Abstract
Objective: Randomised controlled trial (RCT) in adults with anorexia nervosa (AN) showed that Cognitive Remediation Therapy (CRT) enhances cognitive flexibility, abstract thinking and quality‐of‐life. Despite inconsistent findings, CRT has the potential as an adjunct treatment for young people (YP) with AN. A feasibility RCT was conducted in an inpatient setting. The study will also consider the effect of CRT in YP with AN and autistic symptoms. Methods: Participants were randomly allocated to the Immediate or Delayed condition to receive individual CRT sessions, in addition to standard treatment. A repeated measures design was conducted. Results: Eighty participants were recruited. The neuropsychological measures were feasible for evaluating individual CRT in YP. Significant improvements in set‐shifting and central coherence were found, with no main effect between immediate and delayed condition. Significant interactions were found between the condition, and autism spectrum condition (ASC) and No‐ASC subgroup, with significant positive impact of CRT on set‐shifting in the No‐ASC subgroup. There was some evidence that for the No‐ASC subgroup, CRT was more effective if delivered at the start of the treatment; and for the ASC subgroup, that CRT was more effective if delivered at the later stage of treatment. Conclusions: These findings suggest that the overall positive effect of CRT in set‐shifting and central coherence alongside standard treatment. They also indicate the importance of screening for the presence of ASC which could require tailored CRT. Highlights: This feasibility randomised controlled trial (RCT) indicates overall positive effect of Cognitive Remediation Therapy (CRT) in set‐shifting and central coherence alongside standard treatment for inpatient young people (YP) with anorexia nervosa (AN).The study also indicates the importance of screening for the presence of ASC which could require tailored CRT.Further RCT studies are needed to confirm the findings and further explore how CRT can benefit YP with ASC and AN. [ABSTRACT FROM AUTHOR]