학술논문
Two Methods of Whole-Genome Amplification Enable Accurate Genotyping Across a 2320-SNP Linkage Panel.
Document Type
Article
Author
Source
Subject
*GENOMICS
*GENOMES
*MITOCHONDRIAL DNA
*GENETIC polymorphisms
*LINKAGE (Genetics)
*PLOIDY
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Language
ISSN
1088-9051
Abstract
Describes two methods for amplifying whole genomic DNA prior to single nucleotide polymorphism (SNP) analysis. Conversion of fragmented genomic DNA into inherently amplifiable DNA fragments; Multiple displacement amplification (MDA); Chromosome number in SNP linkage; Genotyping concordance for genomic MDA and amplified DNA; Fluorescence imaging system.