학술논문

Rapid and Direct Quantitation of Pharmaceutical Drugs from Urine Using MALDI-MS.
Document Type
Article
Source
LC-GC North America. Mar2013 Current Trends in Mass Spectrometry, Vol. 31, p24-29. 6p.
Subject
*DRUG analysis
*MATRIX-assisted laser desorption-ionization
*URINALYSIS
*METABOLITE analysis
*QUALITATIVE chemical analysis
Language
ISSN
1527-5949
Abstract
The article focuses on a research related to the quantification of drugs from urine using matrix-assisted laser desorption-ionization time-of-flight mass spectrometry (MALDI-TOF-MS). According to the research, linearity was found in concentration ranges of the metabolites found in urine. It also mentions that qualitative analysis of the drugs after LC-MC method was performed using Masslynx 4.1 (Waters) and mMass (open source) software.