학술논문

Plant proteostasis – shaping the proteome: a research community aiming to understand molecular mechanisms that control protein abundance.
Document Type
Article
Source
New Phytologist. Aug2020, Vol. 227 Issue 4, p1028-1033. 6p. 1 Diagram.
Subject
*UBIQUITINATION
*PROTEASOMES
*UNFOLDED protein response
*SCIENTIFIC community
*UBIQUITIN ligases
*PROTEINS
*BIOCHEMISTRY
Language
ISSN
0028-646X
Abstract
Plant proteostasis - shaping the proteome: a research community aiming to understand molecular mechanisms that control protein abundance Keywords: neddylation; plant proteostasis; post-translational modification (PTM) events; protein homeostasis; proteome; SUMOylation; ubiquitination EN neddylation plant proteostasis post-translational modification (PTM) events protein homeostasis proteome SUMOylation ubiquitination 1028 1033 6 07/16/20 20200815 NES 200815 International Conference on Plant Proteostasis, Freiburg, Germany, 10-13 September 2019 One of the major challenges for plant science going forward will be to provide the stability and increase in crop yields required to mitigate against climate change and population growth. The Arabidopsis genome project identified more than a thousand genes encoding components of protein degradation pathways, potentially representing I c. i 8% of the entire plant protein-coding genome, far more than any other eukaryote group, indicating that control of protein stability is a key adaptive trait for plants. Regulating the regulator: governing ubiquitination, SUMOylation and neddylation Ubiquitin and the ubiquitin-like proteins, SUMO and NEDD8, form a family of small proteins that are covalently attached to substrates for the PTM of cellular proteins. [Extracted from the article]