학술논문
Antifungal design: The toxicity-resistance yin-yang.
Document Type
Article
Author
Source
Subject
*AMPHOTERICIN B
*ANTIFUNGAL agents
*DOSE-response relationship in poisons
*DRUG efficacy
*CHEMICAL biology
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*
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Language
ISSN
1552-4450
Abstract
The author discusses research on analogs of the antifungal drug amphotericin B that retain effectiveness with reduced host toxicities, referencing a study by S. A. Davis published in the journal in 2015. Topics covered include the drug's mode of action, as well as the effect of modified antifungal drug on ergosterol and human cholesterol.