학술논문

Pandemic influenza A (2009 H1N1) in children with acute lymphoblastic leukaemia.
Document Type
Article
Source
British Journal of Haematology. Jun2010, Vol. 149 Issue 6, p874-878. 5p. 1 Chart.
Subject
*H1N1 influenza
*LYMPHOBLASTIC leukemia
*CHILDREN
*MECHANICAL ventilators
*VIRUS diseases
Language
ISSN
0007-1048
Abstract
Pandemic influenza A (2009-H1N1) usually results in mild clinical illness, but in some individuals it can be life-threatening. There are no reports of this disease among paediatric patients with acute lymphoblastic leukaemia (ALL). We report ten consecutive patients with ALL and pandemic influenza treated in a single institution. Median age was 7 years (range: 3–12). All were treated with oseltamivir. There were no deaths. Two patients under intensive chemotherapy developed pneumonia and one required ventilatory support. ALL patients under maintenance treatment had mild disease. In conclusion, in our series only patients under intensive treatment developed a moderate to severe disease. [ABSTRACT FROM AUTHOR]