부산대학교 도서관

Summary: This work aimed to evaluate the in vitro adhesive and immunoregulative effects of water‐in‐oil‐in‐water (W/O/W) microencapsulated Lactiplantibacillus plantarum L3 after subjected to yoghurt stress. The W/O/W microencapsulated L. plantarum L3 was prepared and dropped into fresh milk with commercial starters (Streptococcus thermophilus and Lactobacillus delbrueckii subsp. bulgaricus). The yoghurt was prepared and stored at 4 °C for 21 days. The effects of yoghurt storage and simulated gastrointestinal treatment on the in vitro adhesive and immunomodulatory activities of L. plantarum L3 were investigated. Results showed that the hydrophobicity, auto‐aggregation and biofilm synthesis ability of L. plantarum L3 were improved after yoghurt storage but in a storage time‐dependent manner. The maximum coaggregation coefficients with S. aureus and E. coli were higher than 20%. L. plantarum L3 increased the viability and phagocytosis of mouse RAW264.7 cells, whereas the secretion of NO and proinflammatory cytokines induced by LPS was significantly reduced. In conclusion, yoghurt was a promising vehicle for delivering W/O/W L. plantarum L3 to the intestinal tract. [ABSTRACT FROM AUTHOR]