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The best treatment plan requires excellent patient compliance, which can be improved by sufficient communication with the patient during treatment. We need to integrate personalized and standardized treatment before, during and after treatment of I H. pylori i infection, forming a treatment pattern that meets both standards and personalization. Keywords: eradication on primary treatment; Helicobacter pylori; personalized treatment; standardized treatment EN eradication on primary treatment Helicobacter pylori personalized treatment standardized treatment 1 4 4 09/20/22 20221001 NES 221001 INTRODUCTION I Helicobacter pylori i ( I H. pylori i ) was discovered in 1982 by Barry Marshall and Robin Warren, who were awarded the 2005 Nobel Prize in Physiology or Medicine for fundamentally refining the pathogenesis and treatment strategies for chronic active gastritis and peptic ulcer. 32 Gao H, Zhong Z, Yan L, Zhang X, Shen W. Personalized therapy for helicobacter pylori on initial treatment: the initial treatment is the decisive battle. [Extracted from the article]