학술논문
Total Synthesis of Asparenydiol by Two Sonogashira Cross-Coupling Reactions Promoted by Supported Pd and Cu Catalysts.
Document Type
Article
Author
Source
Subject
*SONOGASHIRA reaction
*CATALYST supports
*PALLADIUM catalysts
*CATALYSTS
*COUPLING reactions (Chemistry)
*ETHERIFICATION
*HECK reaction
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Language
ISSN
0039-7881
Abstract
Asparenydiol, which is an important natural compound with potential pharmacological activities, was synthesized through two Sonogashira- cross-coupling reactions catalyzed by supported Pd and Cu catalysts and by a Mitsunobu etherification. The optimization of the Sonogashira- couplings allowed the use of catalysts supported on different matrices with good results in terms of catalytic efficiency and yields. [ABSTRACT FROM AUTHOR]