학술논문

Versatile synthesis of fluorescent, cross-linked peptides as biological probes with the advantage of high helix content.
Document Type
Article
Source
Research on Chemical Intermediates. Jan2013, Vol. 39 Issue 1, p311-319. 9p. 1 Diagram, 1 Chart, 3 Graphs.
Subject
*FLUOROPHORES
*FLUORESCENCE
*PEPTIDE synthesis
*AMINO acids
*ORNITHINE
*MOLECULAR probes
Language
ISSN
0922-6168
Abstract
A variety of fluorophores were introduced at the N-termini of short peptides for use as biological-probes. The fluorescent peptides were cross-linked with a diacetylenic cross-linking agent between the amino acid side chains of ornithine (Orn) residues to produce peptides with high helix content. [ABSTRACT FROM AUTHOR]