학술논문
Detection of an anti-RhD antibody 2 years after sensitization in a patient who had undergone an allogeneic BMT.
Document Type
Article
Author
Source
Subject
*BONE marrow transplantation
*HLA histocompatibility antigens
*IMMUNOGLOBULINS
*GRAFT versus host disease
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Language
ISSN
0268-3369
Abstract
We describe an HLA matched bone marrow transplantation with minor ABO incompatibility and RhD mismatch (donor RhD negative and recipient RhD positive). GVHD appeared on day +96 and therapy with steroid and cyclosporin was started. When GVHD disappeared and immunosuppressive therapy was stopped (2 years after BMT), an anti-RhD antibody was detected in the patient’s serum. The delayed appearance of this antibody may have been associated with the prolonged immunosuppression that was required for treatment of the patient’s GVHD. Bone Marrow Transplantation (2000) 25, 457–459. [ABSTRACT FROM AUTHOR]