학술논문
Lenacapavir with Fostemsavir in a Multidrug-Resistant HIV-Infected Hemodialysis Patient.
Document Type
Case Study
Author
Source
Subject
*HEMODIALYSIS patients
*DRUG side effects
*CHRONIC kidney failure
*HIV-positive persons
*DRUG resistance
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Language
ISSN
2090-6625
Abstract
We report a hemodialysis MDR HIV-infected patient switched to fostemsavir with lenacapavir plus lamivudine for more than a year. She maintained a suppressed viral replication and did not present any clinical or biological drug-related side effects. The combination of lenacapavir plus fostemsavir looks promising in terms of safety and efficacy even in patients with end-stage renal disease awaiting renal transplant. Both drugs are first in class ARVs so that there is no cross resistance with previous drugs, maintaining their efficacy against MDR HIV. [ABSTRACT FROM AUTHOR]