학술논문
Successful large volume leukapheresis on a small infant allogeneic donor.
Document Type
Article
Author
Source
Subject
*STEM cells
*ORGAN donors
*HYPOCALCEMIA
*
*
Language
ISSN
0268-3369
Abstract
We successfully performed a hematopoietic stem cell apheresis on the smallest allogeneic donor reported to date, a 6.1 kg female. After placement of a dialysis catheter in the left femoral vein, the COBE Spectra was primed with one unit of paternal whole blood. Heparin and anticoagulant citrate dextrose, solution A (ACD-A) were slowly administered to the patient. Ionized calcium levels were checked hourly and calcium gluconate was given for hypocalcemia. Coagulation parameters were checked throughout the procedure. We collected 4.4 × 106 CD34+ cells/kg (recipient). The donor tolerated the procedure well and was discharged the following day. Five months later, the child manifests no obvious late effects. Bone Marrow Transplantation (2000) 26, 339–341. [ABSTRACT FROM AUTHOR]