학술논문
Effect of abciximab on prothrombin activation and thrombin generation in patients with acute myocardial infarction also receiving reteplase
Document Type
Article
Author
Source
Subject
*FIBRINOLYSIS
*MYOCARDIAL infarction
*BLOOD coagulation
*BIOMARKERS
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Language
ISSN
0002-9149
Abstract
Fibrinolysis in acute myocardial infarction activates blood coagulation and may favor reocclusion or ischemic complications. The aim of the GUSTO V Italian Hematologic Substudy was to compare the effects of full-dose reteplase on coagulation activation markers with those of half-dose reteplase combined with full-dose abciximab, a platelet glycoprotein IIb/IIIa receptor antagonist, during the early phase after acute myocardial infarction. [Copyright &y& Elsevier]