학술논문

Levels and determinants of breast and cervical cancer screening uptake in HIV-infected women compared with the general population in France.
Document Type
Article
Source
HIV Medicine. Mar2017, Vol. 18 Issue 3, p181-195. 15p.
Subject
*BREAST tumor diagnosis
*HIV infections
*WOMEN
*EARLY detection of cancer
*DIAGNOSIS
CERVIX uteri tumors
Language
ISSN
1464-2662
Abstract
Objectives Cancer is a growing concern for HIV-infected people, and screening plays a major role in alleviating the burden it causes. We sought to investigate the levels and determinants of breast cancer screening ( BCS) and cervical cancer screening ( CCS) in HIV-infected women as compared with the general population. Methods The Agence Nationale de Recherche sur le Sida et les Hépatites Virales ( ANRS)-Vespa2 study was conducted in 2011 in a national representative sample of 3022 HIV-infected hospital out-patients in France. The rates and correlates of BCS and CCS among HIV-infected women were compared with those in the general population using multivariate Poisson regression models. Results The BCS rate during the 2 years preceding the survey interview was 80.7% among HIV-infected women vs. 89.1% in the general population ( P = 0.146). The CCS rate during the preceding 3 years was 88.1% among HIV-infected women vs. 83.1% in the general population ( P = 0.021). During the preceding year, the CCS rate among HIV-infected women was 76.5%. The barriers to BCS and CCS were a low educational level [ BCS: adjusted prevalence rate ratio 0.88; 95% confidence interval ( CI) 0.80-0.97; CCS: adjusted prevalence rate ratio 0.91; 95% CI 0.83-0.99], not having supplementary health insurance ( CCS: adjusted prevalence rate ratio 0.92; 95% CI 0.86-0.98), an irregular gynaecological follow-up ( BCS: adjusted prevalence rate ratio 0.77; 95% CI 0.64-0.92; CCS: adjusted prevalence rate ratio 0.72; 95% CI 0.64-0.81) and a low CD4 count ( BCS: adjusted prevalence rate ratio 0.83; 95% CI 0.71-0.97; CCS: adjusted prevalence rate ratio 0.78; 95% CI 0.63-0.98). The disparities in CCS uptake in terms of age, employment and gynaecological follow-up were less pronounced among HIV-infected women than in the general population. Conclusions BCS and CCS uptake was not lower among HIV-infected women than in the general population, but CCS was suboptimal. Specificities in the profile of barriers to screening emerged. [ABSTRACT FROM AUTHOR]