학술논문
Single-synapse analyses of Alzheimer's disease implicate pathologic tau, DJ1, CD47, and ApoE.
Document Type
Article
Author
Phongpreecha, Thanaphong; Gajera, Chandresh R.; Liu, Candace C.; Vijayaragavan, Kausalia; Chang, Alan L.; Becker, Martin; Fallahzadeh, Ramin; Fernandez, Rosemary; Postupna, Nadia; Sherfield, Emily; Tebaykin, Dmitry; Latimer, Caitlin; Shively, Carol A.; Register, Thomas C.; Craft, Suzanne; Montine, Kathleen S.; Fox, Edward J.; Poston, Kathleen L.; Keene, C. Dirk; Angelo, Michael
Source
Subject
*SYNAPSES
*TAU proteins
*MICROGLIA
*ALZHEIMER'S disease
*CD47 antigen
*APOLIPOPROTEIN E
*GLIAL fibrillary acidic protein
*NEUROFIBRILLARY tangles
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Language
ISSN
2375-2548
Abstract
The article presents a study that explores the single-synapse analyses of Alzheimer's disease, along with mentions the limitation of synaptic molecular characterization for Alzheimer's disease (AD). It discusses about the higher depth and breadth of insight on neurodegenerative diseases obtainable through synaptometry by time of flight (SynTOF).