학술논문
Psychiatric and Medical Profiles of Autistic Adults in the SPARK Cohort.
Document Type
Article
Author
Fombonne, Eric; Green Snyder, LeeAnne; Daniels, Amy; Feliciano, Pamela; Chung, Wendy; The SPARK Consortium; Abbeduto, Leonard; Aberbach, Gabriella; Acampado, John; Ace, Andrea J.; Albright, Charles; Alessandri, Michael; Amaral, David G.; Amatya, Alpha; Anglo, Claudine; Annett, Robert D.; Arriaga, Ivette; Ashley, Raven; Astrovskaya, Irina; Baalman, Kelly
Source
Subject
*MENTAL illness
*AGE distribution
*ARTICULATION disorders
*AUTISM
*CAREGIVERS
*CENTRAL nervous system diseases
*DISEASES
*EATING disorders
*HEALTH status indicators
*LANGUAGE disorders
*LONGITUDINAL method
*PEOPLE with intellectual disabilities
*SEX distribution
*SLEEP disorders
*SPEECH disorders
*DESCRIPTIVE statistics
*
*
*
*
*
*
*
*
*
*
*
*
*
*
*
Language
ISSN
0162-3257
Abstract
This study examined lifetime medical and psychiatric morbidity reported by caregivers of 2917 autistic adults participating in the US research cohort SPARK. Participants were 78.4% male, 47.3% had intellectual disability, and 32.1% had persistent language impairments. Childhood language disorders (59.7%), speech/articulation problems (32.8%), sleep (39.4%) and eating problems (29.4%), motor delays (22.8%) and history of seizure (15.5%) were the most frequently reported clinical features. Over two thirds (67.2%) had been diagnosed with at least one psychiatric disorder (anxiety disorders: 41.1%; ADHD: 38.7%). Compared to verbally fluent participants, those with language impairments had lower frequencies of almost all psychiatric disorders. Female sex and older age were associated with higher medical and psychiatric morbidity. [ABSTRACT FROM AUTHOR]