학술논문

Clinical performance of a novel bioprosthetic surgical aortic valve in a German high‐volume center.
Document Type
Article
Source
Journal of Cardiac Surgery. Dec2022, Vol. 37 Issue 12, p4833-4840. 8p. 5 Charts, 1 Graph.
Subject
*AORTIC valve
*BIOPROSTHETIC heart valves
*AORTIC valve transplantation
*CHRONIC obstructive pulmonary disease
*HEART valves
*HEART valve prosthesis implantation
Language
ISSN
0886-0440
Abstract
Background and Aim: Bioprosthetic surgical aortic valve replacement (SAVR) is increasingly adopted in younger patients. We aimed to analyze mid‐term follow‐up data after SAVR to assess the performance of the prosthesis. Methods: Data were collected from a single‐center series of 154 patients, who underwent SAVR with a bioprosthetic heart valve with the RESILIA tissue at our Heart Centre in Siegburg. All procedural and midterm patient outcomes were documented. Results: Patients had a mean age of 56.8 ± 9.9 years, 35.7% were female, and the mean logistic European system for cardiac operative risk evaluation (EuroSCORE) was 3.4 ± 3.6%. Diabetes (12.3%), atrial fibrillation (10.4%), and chronic obstructive pulmonary disease (COPD) (5.8%) were common comorbidities. The mean surgery duration was 163.8 ± 73.4 min, with the 23 mm (34.4%) and 25 mm (33.8%) heart valves being most frequently implanted. At 3‐year follow‐up, mean pressure gradient was 13.9 ± 5.9 mmHg, peak gradient was 23.6 ± 7.7 mmHg, and effective orifice area (EOA) was 1.9 ± 0.4 cm². No patient died during the operation, 3 (2.1%) patients within 30 days, and 4 (2.7%) thereafter with an overall mortality of n = 7. Of the surviving patients, 97.8% were in New York Heart Association (NYHA) class I/II and none had structural valve deterioration (SVD). Conclusion: Results of our single‐center study indicate favorable procedural outcomes. The safety outcomes confirm preliminary earlier results of this novel bioprosthesis but include more patients and a longer midterm follow‐up. [ABSTRACT FROM AUTHOR]