학술논문

Secondary Osteoporosis: A Still Neglected Condition.
Document Type
Editorial
Source
International Journal of Molecular Sciences. May2023, Vol. 24 Issue 10, p8558. 4p.
Subject
*FRACTURE healing
*BONE resorption
*OSTEOPOROSIS
*BONE morphogenetic protein receptors
*METABOLIC bone disorders
Language
ISSN
1661-6596
Abstract
The idea that bone could be a target tissue in many systemic disorders has fostered the evaluation of bone health in patients affected by disorders previously not known to be associated with bone consequences. The condition of "secondary osteoporosis" is defined as a bone loss that results from specific well-defined clinical disorders [[1]]. In this regard, the Special Issue, Secondary Osteoporosis 2.0, includes a thorough review of the clinical bone phenotypes and the associated bone fragility in rare congenital metabolic bone disorders, following a disease taxonomic classification based on deranged bone metabolic activity. While waiting for the advances in bone research, physicians should always consider that an unexplainable bone fragility could be the sole and the presenting symptom of an otherwise silent disease, and that in patients with a known chronic disorder, bone health should be evaluated for the other target organs of our body. [Extracted from the article]