학술논문
Acute lung injury after platelet transfusion in a patient with dengue fever.
Document Type
Article
Author
Source
Subject
*LUNG injuries
*BLOOD testing
*BLOOD transfusion reaction
*BLOOD gases analysis
*BLOOD platelet transfusion
*CHEST X rays
*ECHOCARDIOGRAPHY
*ELECTROCARDIOGRAPHY
*MICROBIAL sensitivity tests
*PHYSICAL diagnosis
*PULMONARY edema
*SOCIAL services case management
*DENGUE hemorrhagic fever
*DISEASE complications
*INJURY risk factors
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Language
ISSN
0973-6247
Abstract
Transfusion-related acute lung injury (TRALI) is a serious clinical syndrome associated with the transfusion of plasma-containing blood components. Recently, TRALI has come to be recognized as the leading cause of transfusion-related mortality. This complication typically presents as shortness of breath, hypoxemia, hypotension, fever, and non cardiogenic pulmonary edema, occurring within 6 h after transfusion. Although the mechanism of TRALI has not been exactly known, it has been associated with human leukocyte antigen antibodies and with biologically active mediators in stored cellular blood components. We, hereby, present a case of a patient with dengue fever who developed acute lung injury (ALI), presumably TRALI, after transfusion of platelet concentrates. He was treated with supportive measures and mechanical ventilation. Greater knowledge and increased awareness especially amongst the clinicians regarding TRALI is needed for prevention and treatment of this potentially severe complication of blood/component transfusion. [ABSTRACT FROM AUTHOR]