학술논문

Human papillomavirus tumour status is not associated with a positive depression screen for patients with oropharyngeal cancer.
Document Type
Article
Source
Journal of Laryngology & Otology. Sep2017, Vol. 131 Issue 9, p760-767. 8p.
Subject
*DIAGNOSIS of mental depression
*MENTAL depression risk factors
*HEAD tumors
*NECK tumors
*BLACK people
*CANCER patients
*DEMOGRAPHY
*MEDICAL screening
*PAPILLOMAVIRUS diseases
*QUESTIONNAIRES
*SQUAMOUS cell carcinoma
*WHITE people
*DATA analysis software
*DISEASE complications
*OROPHARYNGEAL cancer
*DIAGNOSIS
*CANCER treatment
Language
ISSN
0022-2151
Abstract
Background:Several risk factors for depression in patients with oropharyngeal cancer have been determined. However, it is unknown whether human papillomavirus associated oropharyngeal cancer, which has a distinct clinico-demographic profile, modulates this risk.Methods:A retrospective analysis was conducted of patients with oropharyngeal cancer. These patients had completed a 10-item depression screening questionnaire before receiving treatment for their disease from 2011 to 2014. Associations between patient or disease characteristics and depression screening questionnaire results were investigated.Results:The study comprised 69 patients, 31 (44.9 per cent) of whom screened positive for depression. There were no significant differences in distributions of clinico-demographic or histopathological characteristics, including human papillomavirus tumour status, by depression screen result.Conclusion:This population has a high risk for depression, but no obvious risk factors, including human papillomavirus tumour status, were associated with an elevated risk. This inability to risk-stratify patients by clinico-demographic or disease characteristics emphasises the importance of regular depression screening for all patients in this population. [ABSTRACT FROM AUTHOR]