학술논문
Evolving blood pressure dynamics for extremely preterm infants.
Document Type
Article
Author
Source
Subject
*ARTERIES
*BLOOD pressure
*PREMATURE infants
*INFANT development
*LONGITUDINAL method
*SCIENTIFIC observation
*RESEARCH funding
*DESCRIPTIVE statistics
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Language
ISSN
0743-8346
Abstract
Objective:To examine changes in arterial blood pressure (ABP) after birth in extremely preterm infants.Study Design:Prospective observational study of infants 230/7 to 266/7 weeks gestational age (GA). Antihypotensive therapy use and ABP measurements were recorded for the first 24 h.Result:A cohort of 367 infants had 18 709 ABP measurements recorded. ABP decreased for the first 3 h, reached a nadir at 4 to 5 h and then increased at an average rate of 0.2 mm Hg h−1. The rise in ABP from hour 4 to 24 was similar for untreated infants (n=164) and infants given any antihypotensive therapy (n=203), a fluid bolus (n=135) or dopamine (n=92). GA-specific trends were similar. ABP tended to be lower as GA decreased, but varied widely at each GA.Conclusion:ABP increased spontaneously over the first 24 postnatal hours for extremely preterm infants. The rate of rise in ABP did not change with antihypotensive therapy. [ABSTRACT FROM AUTHOR]