학술논문

Disseminated Scopulariopsis–culture is required to distinguish from other disseminated mould infections.
Document Type
Article
Source
Journal of Cutaneous Pathology. Jun2010, Vol. 37 Issue 6, p687-691. 5p. 4 Color Photographs, 1 Chart.
Subject
*MYCOSES
*BONE marrow transplantation
*ONYCHOMYCOSIS
*MOLDS (Fungi)
*IMMUNE system
*FUSARIUM
Language
ISSN
0303-6987
Abstract
Disseminated fungal infections are a major cause of mortality in severely immunocompromised bone marrow transplant (BMT) patients. Scopulariopsis is a soil saprophytic mould that is typically associated with onychomycosis and only rarely associated with disseminated infection with cutaneous findings. We describe a case of fatal disseminated Scopulariopsis infection in a 56-year-old neutropenic male with chronic myelogenous leukemia status post peripheral blood stem cell transplant that was clinically and histologically indistinguishable from disseminated Aspergillus, Fusarium or zygomycosis infection. Distinguishing the above listed fungi by tissue culture is crucial because disseminated Scopulariopsis is difficult to eradicate and associated with a high mortality rate in the immunocompromised BMT patient population. Swick BL, Reddy SC, Friedrichs A, Stone MS. Disseminated Scopulariopsis–culture is required to distinguish from other disseminated mould infections. [ABSTRACT FROM AUTHOR]