학술논문

Influence of increased body mass index on drug toxicity in patients with acute promyelocytic leukemia.
Document Type
Case Study
Source
Leukemia (08876924). Sep98, Vol. 12 Issue 9, p1503-1506. 4p.
Subject
*DRUG toxicity
*ACUTE leukemia
*PHARMACEUTICAL arithmetic
*BODY weight
*OBESITY complications
*ANTIMETABOLITES
*ANTINEOPLASTIC agents
*ANTINEOPLASTIC antibiotics
*DAUNOMYCIN
*HEART
*HEART failure
*HETEROCYCLIC compounds
*LYMPHOBLASTIC leukemia
*TRETINOIN
*BODY mass index
*DISEASE remission
*CYTARABINE
*ACUTE promyelocytic leukemia
*DISEASE complications
Language
ISSN
0887-6924
Abstract
Focuses on the influence of increased mass index on drug toxicity in patients with acute promyelocytic leukemia. Calculation of the drug dose used in the treatment of leukemia; Cause of a cardiac toxic reaction by the anthracycline antibiotics; Development of a cardiac toxicity due to cumulative injury to the myocardium; Method of determining drug doses in obese leukemic patients.