학술논문
Neurophysiological challenges in myasthenia gravis associated with MuSK antibodies: a case report.
Document Type
Article
Source
Subject
*MYASTHENIA gravis
*ACTION potentials
*MOTOR unit
*IMMUNOGLOBULINS
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Language
ISSN
1590-1874
Abstract
Repetitive nerve stimulation (RNS) in limb muscles has low sensitivity in myasthenia gravis with muscle-specific tyrosine kinase antibodies (MuSK-MG) given the predominant involvement of cranial and neck muscles [[1]]. MG was diagnosed after single-fiber EMG (SF-EMG) of the frontalis muscle showed increased jitter (no details available) and serum MuSK antibody (Ab) was detected by standard radioimmunoassay (RIA) (1.12 nMol/L, reference < 0.05). Needle electromyography (EMG) of the deltoid muscle showed polyphasic motor unit action potentials (MUAPs) of reduced amplitude associated with fibrillation potentials; 3 Hz RNS of the axillary nerve did not show a decremental pattern. [Extracted from the article]