학술논문
Comparative effects of lifestyle modification, metformin and exenatide/glargine combination therapy on daily glycaemic fluctuation in the setting of near‐normoglycaemia.
Document Type
Article
Author
Source
Subject
*INSULIN aspart
*METFORMIN
*GLYCEMIC index
*GLUCAGON-like peptide-1 receptor
*GLYCEMIC control
*GLUCAGON-like peptide-1 agonists
*TYPE 2 diabetes
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Language
ISSN
1462-8902
Abstract
While FLAT-SUGAR and other studies[[2], [4]] have shown that a basal insulin and GLP-1 agonist combination therapy can reduce glycaemic variability in patients with suboptimal glycaemic control and longstanding T2D, little is known about whether this capacity would be relevant in the setting of near-normoglycaemia in early T2D. The patient is a 57-year-old male with T2D of 6 years' duration, who was participating in the PREserVing beta-cell function in type 2 diabetes with exenatide And InsuLin B ( b PREVAIL) trial (ClinicalTrials.Gov NCT02194595). Glucose variability in a 26-week randomized comparison of mealtime treatment with rapid-acting insulin versus GLP-1 agonist in participants with type 2 diabetes at high cardiovascular risk. [Extracted from the article]