학술논문
Regulation of mitochondrial temperature in health and disease.
Document Type
Article
Author
Source
Subject
*TEMPERATURE control
*OXIDATIVE phosphorylation
*HIGH temperatures
*HEAT shock proteins
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Language
ISSN
0031-6768
Abstract
Mitochondrial temperature is produced by various metabolic processes inside the mitochondria, particularly oxidative phosphorylation. It was recently reported that mitochondria could normally operate at high temperatures that can reach 50℃. The aim of this review is to identify mitochondrial temperature differences between normal cells and cancer cells. Herein, we discussed the different types of mitochondrial thermosensors and their advantages and disadvantages. We reviewed the studies assessing the mitochondrial temperature in cancer cells and normal cells. We shed the light on the factors involved in maintaining the mitochondrial temperature of normal cells compared to cancer cells. [ABSTRACT FROM AUTHOR]