학술논문

Mindfulness instruction for medication adherence among adolescents and young adults living with HIV: a randomized controlled trial.
Document Type
Article
Source
AIDS Care. Dec2022, Vol. 34 Issue 12, p1619-1627. 9p. 1 Diagram, 5 Charts, 1 Graph.
Subject
*HIV infection transmission
*MINDFULNESS
*HIV-positive persons
*HIV infections
*HEALTH education
*PATIENTS' attitudes
*RANDOMIZED controlled trials
*TREATMENT effectiveness
*COMPARATIVE studies
*STRESS management
*DRUGS
*DESCRIPTIVE statistics
*PATIENT compliance
*STATISTICAL sampling
*COGNITIVE therapy
*ADULTS
*ADOLESCENCE
Language
ISSN
0954-0121
Abstract
Adolescents and young adults (AYA) 13–24 years old make up a disproportionate 21% of new HIV diagnoses. Unfortunately, they are less likely to treat HIV effectively, with only 30% achieving viral suppression, limiting efforts to interrupt HIV transmission. Previous work with mindfulness-based stress reduction (MBSR) has shown promise for improving treatment in AYA living with HIV (AYALH). This randomized controlled trial compared MBSR with general health education (HT). Seventy-four 13–24-year-old AYALH conducted baseline data collection and were randomized to nine sessions of MBSR or HT. Data were collected at baseline, post-program (3 months), 6 and 12 months on mindfulness and HIV management [medication adherence (MA), HIV viral load (HIV VL), and CD4]. Longitudinal analyses were conducted. The MBSR arm reported higher mindfulness at baseline. Participants were average 20.5 years old, 92% non-Hispanic Black, 51% male, 46% female, and 3% transgender. Post-program, MBSR participants had greater increases than HT in MA (p = 0.001) and decreased HIV VL (p = 0.052). MBSR participants showed decreased mindfulness at follow-up. Given the significant challenges related to HIV treatment in AYALH, these findings suggest that MBSR may play a role in improving HIV MA and decreasing HIV VL. Additional research is merited to investigate MBSR further for this important population. [ABSTRACT FROM AUTHOR]