학술논문
Long-read genome assemblies for the study of chromosome expansion: Drosophila kikkawai, Drosophila takahashii, Drosophila bipectinata, and Drosophila ananassae.
Document Type
Article
Author
Source
Subject
*DROSOPHILA
*DROSOPHILA melanogaster
*CHROMOSOMES
*GENOME size
*GENOMES
*NUCLEOTIDE sequencing
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Language
ISSN
2160-1836
Abstract
Flow cytometry estimates of genome sizes among species of Drosophila show a 3-fold variation, ranging from ~127 Mb in Drosophila mercatorum to ~400 Mb in Drosophila cyrtoloma. However, the assembled portion of the Muller F element (orthologous to the fourth chromosome in Drosophila melanogaster) shows a nearly 14-fold variation in size, ranging from ~1.3 Mb to >18 Mb. Here, we present chromosome-level long-read genome assemblies for 4 Drosophila species with expanded F elements ranging in size from 2.3 to 20.5 Mb. Each Muller element is present as a single scaffold in each assembly. These assemblies will enable new insights into the evolutionary causes and consequences of chromosome size expansion. [ABSTRACT FROM AUTHOR]