부산대학교 도서관

Mechanisms of inhibiting neutrophil degranulation Inhibiting neutrophil degranulation can promote bacterial survival by preventing the targeting of antimicrobial proteins either intracellularly to the phagosome or extracellularly to the plasma membrane. Mechanisms of inducing neutrophil degranulation While several pathogens inhibit neutrophil degranulation to promote survival, there are instances of bacteria that induce granule exocytosis. Outcomes of modulating neutrophil degranulation Typically, microorganisms that inhibit neutrophil degranulation have greater survival following interactions with neutrophils. Effects of tissue environment on neutrophil degranulation Many studies that analyze neutrophil degranulation use freshly isolated neutrophils and a mono-infection tissue culture assay, and these experiments are critical to our understanding of neutrophil degranulation mechanisms. [Extracted from the article]