학술논문

Rapidly progressive cutaneous Rhizopus microsporus infection presenting as Fournier's gangrene in a patient with acute myelogenous leukemia.
Document Type
Article
Source
Transplant Infectious Disease. Aug2011, Vol. 13 Issue 4, p392-396. 5p. 2 Color Photographs.
Subject
*CASE studies
*FOURNIER gangrene
*ZYGOMYCETES
*MUCORMYCOSIS
*ACUTE myeloid leukemia
Language
ISSN
1398-2273
Abstract
C.M. Durand, C.D. Alonso, A.P. Subhawong, N.P. Kwiatkowski, M. Showel, K.C. Carroll, K.A. Marr. Rapidly progressive cutaneous Rhizopus microsporus infection presenting as Fournier's gangrene in a patient with acute myelogenous leukemia. Transpl Infect Dis 2011: 13: 392-396. All rights reserved Abstract: Members of the genus Rhizopus within the class Zygomycetes can cause devastating opportunistic infections. Cutaneous disease arising from direct inoculation of fungal spores has the potential to disseminate widely. Here, we describe a dramatic case of cutaneous Rhizopus infection involving the penis in a patient with acute myelogenous leukemia. Despite aggressive surgical debridement, systemic antifungal therapy, and donor lymphocyte infusion, the infection was ultimately fatal. This case illustrates the unique diagnostic and therapeutic challenges in the clinical management of cutaneous Rhizopus infection. [ABSTRACT FROM AUTHOR]