학술논문

Evaluation of the MTS™ aztreonam-avibactam strip (Liofilchem) on New Delhi metallo-β-lactamase-producing Enterobacterales.
Document Type
Article
Source
European Journal of Clinical Microbiology & Infectious Diseases. Apr2024, Vol. 43 Issue 4, p777-784. 8p.
Subject
*TEST methods
*AZTREONAM
*AUTOMATED teller machines
*DILUTION
Language
ISSN
0934-9723
Abstract
The combination of ceftazidime-avibactam (CAZ-AVI) and aztreonam (ATM) is used to treat MBL-producing Enterobacterales-related infections. The new combination aztreonam-avibactam (AZA) is currently in development. We compared results obtained with the new MIC test strip (MTS) AZA (Liofilchem) with broth microdilution method (BMD) on 41 MBL-producing Enterobacterales from 41 clinical samples. The MTS AZA was also compared to combination testing method using CAZ-AVI and ATM strips. Compared to BMD, categorical agreement (CA) was 100%. Compared with combination testing method, CA was 97.6%. The MTS AZA can be used to determine MICs levels of AZA or CAZ-AVI/ATM combinations. [ABSTRACT FROM AUTHOR]