학술논문
Angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor blockers after renal transplantation.
Document Type
Article
Author
Source
Subject
*ANGIOTENSIN converting enzyme
*LIVER transplantation
*HEART transplant recipients
*CHRONIC kidney failure
*HEART diseases
*HOMOGRAFTS
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Language
ISSN
0902-0063
Abstract
Renin-angiotensin system blockade retards the progression of diabetic and non-diabetic chronic kidney disease of the native kidneys. Though most patients suffer from a significant renal insufficiency (chronic kidney disease stage III) and a concomitant heart disease after renal transplantation, there is up to now no evidence supporting the use of inhibitors of the renin-angiotensin system in these patients. We wish to summarize the available evidence on the use of inhibitors of the renin-angiotensin system after renal transplantation. We specifically discuss potential beneficial as well as adverse effects of a renin-angiotensin system blockade. In addition, we review their influence on morphologic and biochemical markers as well as on renal function, graft and patient survival after renal transplantation. [ABSTRACT FROM AUTHOR]