부산대학교 도서관

Aim,materials and methods: To find gender-related differences in blood pressure (BP) and urinary chloride excretion as well as a relation between them, we monitored diurnal, overnight, and 24-h urinary chloride as well as BP hourly in 22 adolescent males and 22 adolescent females. To show a possible influence of sexual hormones on chloride excretion and BP, we also monitored 15 adolescent females during different phases of their menstrual cycle. Results: The over- night systolic and pulse BP was significantly higher in males than in females. The diurnal pulse BP was significantly higher in males than in females at the beginning of follicular phase. The diurnal systolic, diastolic, and mean BP was significantly higher than nocturnal in all the groups studied. The overnight urinary chloride level in females at the beginning of the follicular phase was significantly lower than during ovulation. Urinary chloride level during luteal phase was comparable with that during ovulation. The total 24-h urinary chloride in the general group of males was significantly higher than in females at the beginning of follicular phase. In the general group of females, diurnal urinary chloride excretion negatively correlated with diastolic and mean BP, but such a correlation was absent in males. Overnight, on the contrary, the correlation between urinary chloride excretion and BP was absent in females, but it was positive in males. The diurnal and overnight urinary chloride excretion exhibited a negative correlation with BP in females during luteal phase. A correlation between overnight chloride excretion and mean BP was positive in males, but negative in females during luteal phase. Conclusion: BP, urinary chloride excretion, and relation between them in adolescents are gender- and circadian cycle- related. Sexual hormones may play a role both in regulation of BP and urinary chloride excretion. [ABSTRACT FROM AUTHOR]