학술논문
Perioperative retinoic acid syndrome in a patient with acute promyelocytic leukemia
Document Type
Article
Author
Source
Subject
*ACUTE promyelocytic leukemia
*TRETINOIN
*RETINOIDS
*DRUG therapy
*DEXAMETHASONE
*DRUG side effects
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Language
ISSN
0952-8180
Abstract
Abstract: All-trans retinoic acid (ATRA), a vitamin A derivative, is prescribed for induction of chemotherapy in patients with acute promyelocytic leukemia. Like other chemotherapy agents, ATRA has an adverse effect known as retinoic acid syndrome. The case of a 22 year old woman with acute promyelocytic leukemia, who received ATRA and subsequently developed retinoic acid syndrome, is presented. The patient''s symptoms resolved after administration of dexamethasone, allowing the completion of chemotherapy without further complications. [Copyright &y& Elsevier]