학술논문
Patent Foramen Ovale Percutaneous Closure: Evolution and Ongoing Challenges.
Document Type
Article
Source
Subject
*PATENT foramen ovale
*ISCHEMIC stroke
*PLATYPNEA orthodeoxia syndrome
*CLINICAL trials
*STROKE
*DECOMPRESSION sickness
*VENTRICULAR septal defects
*
*
*
*
*
*
Language
ISSN
2077-0383
Abstract
Patent foramen ovale (PFO) concerns nearly a quarter of the general population and incidence may reach up to 50% in patients with cryptogenic stroke. Recent randomized clinical trials confirmed that percutaneous closure of PFO-related stroke reduces the risk of embolic event recurrence. PFO also comes into play in other pathogenic conditions, such as migraine, decompression sickness or platypnea–orthodeoxia syndrome, where the heterogeneity of patients is high and evidence for closure is less well-documented. In this review, we describe the current indications for PFO percutaneous closure and the remaining challenges, and try to provide future directions regarding the technique and its indications. [ABSTRACT FROM AUTHOR]