학술논문

Investigating metabolic regulation using targeted neuromodulation.
Document Type
Article
Source
Annals of the New York Academy of Sciences. Jan2018, Vol. 1411 Issue 1, p83-95. 13p. 3 Diagrams, 1 Chart.
Subject
*METABOLIC regulation
*NEURAL circuitry
*ENERGY metabolism
*OPTOGENETICS
*RADIOGENETICS
Language
ISSN
0077-8923
Abstract
Abstract: The central nervous system (CNS) plays a vital role in regulating energy balance and metabolism. Over the last 50 years, studies in animal models have allowed us to identify critical CNS regions involved in these processes and even crucial cell populations. Now, techniques for genetically and anatomically targeted manipulation of specific neural populations using light (optogenetic), ligands (chemogenetic), or magnetic fields (radiogenetic/magnetogenetic) allow detailed investigation of circuits involved in metabolic regulation. In this review, we provide a brief overview of recent studies using light‐ and magnetic field–regulated neural activity to investigate the neural circuits contributing to metabolic control. [ABSTRACT FROM AUTHOR]