학술논문

Improved Efficiency of Budesonide Nebulization Using Surface-Active Agents.
Document Type
Article
Source
Drug Delivery. Sep-Oct2006, Vol. 13 Issue 5, p357-363. 6p. 2 Charts, 3 Graphs.
Subject
*SURFACE active agents
*DETERGENTS
*ADRENOCORTICAL hormones
*THERAPEUTICS
*BRONCHIAL diseases
*AEROSOLS
Language
ISSN
1071-7544
Abstract
Our aim was to improve the efficiency of nebulised budesonide using surface-active agents. Cationic, anionic, and nonionic detergents were added to commercial budesonide suspension, and the particle size distribution during nebulization was measured using both cascade impaction and laser diffraction. Our results showed that the emitted dose was increased after addition of cationic ( p [ABSTRACT FROM AUTHOR]