학술논문
Protective action of n-3 fatty acids on benzo[a]pyrene-induced apoptosis through the plasma membrane remodeling-dependent NHE1 pathway.
Document Type
Article
Author
Dendelé, Béatrice; Tekpli, Xavier; Hardonnière, Kévin; Holme, Jørn A.; Debure, Laure; Catheline, Daniel; Arlt, Volker M.; Nagy, Eszter; Phillips, David H.; Øvrebø, Steinar; Mollerup, Steen; Poët, Mallory; Chevanne, Martine; Rioux, Vincent; Dimanche-Boitrel, Marie-Thérèse; Sergent, Odile; Lagadic-Gossmann, Dominique
Source
Subject
*OMEGA-3 fatty acids
*BENZOPYRENE
*APOPTOSIS
*CELL membranes
*ALKALINIZATION
*CYTOCHROME P-450
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Language
ISSN
0009-2797
Abstract
Highlights: [•] Omega-3 inhibit B[a]P-induced apoptosis in liver cells. [•] Omega-3 induce plasma membrane remodeling in liver cells. [•] Omega-3 inhibit B[a]P-induced intracellular alkalinization in liver cells. [Copyright &y& Elsevier]