학술논문
A microbial-derived succinylated bile acid to safeguard liver health.
Document Type
Article
Source
Subject
*BILE acids
*CHOLIC acid
*CELLULAR signal transduction
*LIVER diseases
*AUTHORSHIP collaboration
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Language
ISSN
0092-8674
Abstract
In this issue of Cell , Nie and co-authors report that the microbe-derived bile acid (BA) 3-succinylated cholic acid protects against the progression of metabolic dysfunction-associated liver disease. Intriguingly, its protective mechanism does not involve traditional BA signaling pathways but is instead linked to the proliferation of the commensal microbe Akkermansia muciniphila. [ABSTRACT FROM AUTHOR]